IL-1b and TGF-b Act Antagonistically in Induction and Differentially in Propagation of Human Proinflammatory Precursor CD4 T Cells
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منابع مشابه
IL-1β and TGF-β act antagonistically in induction and differentially in propagation of human proinflammatory precursor CD4+ T cells.
Cytokines are critical messengers that control the differentiation of Th cells. To evaluate their impact on the fate of human naive CD4(+) T cells from cord and adult blood, early T cell differentiation was monitored after T cell activation in the presence of pro- and anti-inflammatory cytokines. Interestingly, the analysis of Th cell lineage-specific molecules revealed that IL-1β on its own me...
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تاریخ انتشار 2011